Mark Cook

MBBS (Melbourne), MD (London)
Chair of Medicine at St Vincent’s Hospital (Melbourne)

Currently Chair of Medicine at St. Vincent’s Hospital, Professor Cook specialises in the treatment of epilepsy and his previous role was also at St Vincent’s as Professor and Director of Neurology. He is recognised internationally for his expertise in epilepsy management, particularly imaging and surgical planning.
After completing specialist training in Melbourne, he undertook an MD thesis while working as Brain Research Fellow at Queen Square, London. He returned to St. Vincent’s Hospital, Melbourne to continue his interest in neuroimaging in epilepsy.
Under his directorship, both the research and clinical components of the Neurology Department at St Vincent’s have been significantly enlarged. Currently one of the largest units in Australia for the surgical treatment of epilepsy, this was a direct extension of work he began in London, where he developed techniques for the accurate measurement of hippocampal volumes, and established their position in non-invasive assessment of surgical candidates. More recently his interests have included experimental models of epilepsy and seizure prediction.

Research fields of interest

  • implantable devices 
  • epilepsy


  1. Carne, R. P., O'Brien, T. J., Kilpatrick, C. J., MacGregor, L. R., Hicks, R. J., Murphy, M. A., et al. (2004). MRI-negative PET-positive temporal lobe epilepsy: a distinct surgically remediable syndrome. Brain, 127, 2276-2285.

  2. Cendes, F., Cook, M. J., Watson, C., Andermann, F., Fish, D. R., Shorvon, S. D., et al. (1995). FREQUENCY AND CHARACTERISTICS OF DUAL PATHOLOGY IN PATIENTS WITH LESIONAL EPILEPSY. Neurology, 45(11), 2058-2064.

  3. Cook, M. J., Fish, D. R., Shorvon, S. D., Straughan, K., & Stevens, J. M. (1992). HIPPOCAMPAL VOLUMETRIC AND MORPHOMETRIC STUDIES IN FRONTAL AND TEMPORAL-LOBE EPILEPSY. Brain, 115, 1001-1015.

  4. Free, S. L., Bergin, P. S., Fish, D. R., Cook, M. J., Shorvon, S. D., & Stevens, J. M. (1995). METHODS FOR NORMALIZATION OF HIPPOCAMPAL VOLUMES MEASURED WITH MR. American Journal of Neuroradiology, 16(4), 637-643.

  5. Li, L. M., Cendes, F., Andermann, F., Watson, C., Fish, D. R., Cook, M. J., et al. (1999). Surgical outcome in patients with epilepsy and dual pathology. Brain, 122, 799-805.

  6. Obrien, T. J., Newton, M. R., Cook, M. J., Berlangieri, S. U., Kilpatrick, C., Morris, K., et al. (1997). Hippocampal atrophy is not a major determinant of regional hypometabolism in temporal lobe epilepsy. Epilepsia, 38(1), 74-80.

  7. Raymond, A. A., Fish, D. R., Stevens, J. M., Cook, M. J., Sisodiya, S. M., & Shorvon, S. D. (1994). ASSOCIATION OF HIPPOCAMPAL SCLEROSIS WITH CORTICAL DYSGENESIS IN PATIENTS WITH EPILEPSY. Neurology, 44(10), 1841-1845.

  8. Raymond, A. A., Halpin, S. F. S., Alsanjari, N., Cook, M. J., Kitchen, N. D., Fish, D. R., et al. (1994). DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR - FEATURES IN 16 PATIENTS. Brain, 117, 461-475.

  9. Vajda, F. J., O'Brien, T. J., Hitchcock, A., Graham, J., Cook, M., Lander, C., et al. (2004). Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy. Journal of Clinical Neuroscience, 11(8), 854-858.

  10. Li, L. M., Cendes, F., Watson, C., Andermann, F., Fish, D. R., Dubeau, F., et al. (1997). Surgical treatment of patients with single and dual pathology: Relevance of lesion and of hippocampal atrophy to seizure outcome. Neurology, 48(2), 437-444.
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