Mr Nicholas Sinclair

Senior Research Engineer, PhD Researcher BEng (Hons), BSc (Swinburne University)

Mr Nicholas Sinclair

Nicholas joined the Bionics Institute in 2010 as part of the multi-disciplinary team developing a bionic eye. In that role, he developed neurostimulation and psychophysics equipment and performed experiments with bionic eye implantees. Following the successful completion of the first-in-human trial of a suprachoroidal retinal prosthesis, Nicholas moved to the Neurobionics team where he now works on improving Deep Brain Stimulation therapy for Parkinson’s disease and other conditions and is also undertaking a part-time PhD in this area. Prior to joining the Bionics Institute, Nicholas spent several years developing an EEG-based depth of anaesthesia monitor.

Research fields of interest

  • Neurostimulation
  • Biosignals
  • Development of medical bionics devices
  • Biomedical engineering

Research projects

Selected Publications

  1. Shivdasani, M. N., N. C. Sinclair, L. N. Gillespie, M. A. Petoe, S. A. Titchener, J. B. Fallon, T. Perera, D. Pardinas-Diaz, N. M. Barnes, and P. J. Blamey. 2017. Identification of Characters and Localization of Images Using Direct Multiple-Electrode Stimulation With a Suprachoroidal Retinal Prosthesis. Investigative Ophthalmology & Visual Science. 58(10): 3962-74. Full Text
  2. Petoe, M. A., C. D. McCarthy, M. N. Shivdasani, N. C. Sinclair, A. F. Scott, L. N. Ayton, N. M. Barnes, R. H. Guymer, P. J. Allen, P. J. Blamey, and Consortium Bionic Vision Australia. 2017. Determining the Contribution of Retinotopic Discrimination to Localization Performance With a Suprachoroidal Retinal Prosthesis. Investigative Ophthalmology & Visual Science. 58(7): 3231-39. Full Text
  3. Sinclair, N. C., M. N. Shivdasani, T. Perera, L. N. Gillespie, H. J. McDermott, L. N. Ayton, and P. J. Blamey. 2016. The Appearance of Phosphenes Elicited Using a Suprachoroidal Retinal Prosthesis. Investigative Ophthalmology & Visual Science. 57(11): 4948-61. Full Text
  4. Barnes, N., A. F. Scott, P. Lieby, M. A. Petoe, C. McCarthy, A. Stacey, L. N. Ayton, N. C. Sinclair, M. N. Shivdasani, N. H. Lovell, H. J. McDermott, and J. G. Walker. 2016. Vision function testing for a suprachoroidal retinal prosthesis: effects of image filtering. Journal of Neural Engineering. 13(3): 036013.
  5. Slater, K. D., N. C. Sinclair, T. S. Nelson, P. J. Blamey, and H. J. McDermott. 2015. neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications. IEEE Journal of Translational Engineering in Health and Medicine. 3: e3800111. Full Text
  6. Shivdasani, M. N., N. C. Sinclair, P. N. Dimitrov, M. Varsamidis, L. N. Ayton, C. D. Luu, T. Perera, H. J. McDermott, and P. J. Blamey. 2014. Factors affecting perceptual thresholds in a suprachoroidal retinal prosthesis. Investigative Ophthalmology & Visual Science. 55(10): 6467-81. Full Text
  7. Ayton, L. N., P. J. Blamey, R. H. Guymer, C. D. Luu, D. A. Nayagam, N. C. Sinclair, M. N. Shivdasani, J. Yeoh, M. F. McCombe, R. J. Briggs, N. L. Opie, J. Villalobos, P. N. Dimitrov, M. Varsamidis, M. A. Petoe, C. D. McCarthy, J. G. Walker, N. Barnes, A. N. Burkitt, C. E. Williams, R. K. Shepherd, and P. J. Allen. 2014. First-in-human trial of a novel suprachoroidal retinal prosthesis. PLoS ONE. 9(12): e115239. Full Text
  8. De Silva, A. C., N. C. Sinclair, and D. T. Liley. 2012. Limitations in the rapid extraction of evoked potentials using parametric modeling. IEEE Transactions on Bio-medical Engineering. 59(5): 1462-71. doi: 10.1109/TBME.2012.2188527. Full Text
  9. Liley, D. T., N. C. Sinclair, T. Lipping, B. Heyse, H. E. Vereecke, and M. M. Struys. 2010. Propofol and remifentanil differentially modulate frontal electroencephalographic activity. Anesthesiology. 113(2): 292-304. doi: 10.1097/ALN.0b013e3181e3d8a6. Full Text
  10. Liley, D. T., K. Leslie, N. C. Sinclair, and M. Feckie. 2008. Dissociating the effects of nitrous oxide on brain electrical activity using fixed order time series modeling. Computers in Biology and Medicine. 38(10): 1121-30. doi: 10.1016/j.compbiomed.2008.08.011.

See more publications by Nicholas Sinclair in PubMed

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