RachaelRichardson

Dr Rachael Richardson

Senior Research Fellow, Bionics Institute BSc (Hons), PhD

Dr Rachael Richardson

Dr Rachael Richardson is a Senior Research Fellow at the Bionics Institute. She has a background in molecular biology (Walter and Eliza Hall Institute) and hearing science (Bionics Institute). Her current research projects have the common goal of protecting and regenerating sensory cells in the cochlea after hearing loss. She is interested in the use of gene therapy techniques to express therapeutic proteins such as neurotrophins and transcription factors in specific cells of the cochlea. These factors have the potential to protect cochlear neurons and hair cells and even to promote the regeneration of these cells after hearing loss. Her work is published in high ranking peer reviewed journals.

Dr Richardson collaborates with senior researchers in the field of cochlear implantation, hearing research and biomedical engineering, including Prof. Stephen O’Leary, Prof Paul Stoddart, Dr Andrew Wise and Dr James Fallon. She collaborates with research leaders from the University of Washington, Swinburne University and the University of Wollongong. She supervises PhD, honours and undergraduate students and is currently accepting new students.

Dr Richardson receives funding from the NHMRC, Action on Hearing Loss (UK) and the Garnett Passe and Rodney Williams Memorial Foundation (Australia).

Research fields of interest

  • Protecting and regenerating sensory cells (auditory nerves and cochlear hair cells) after hearing loss

  • Gene therapy in the cochlea

  • Protection of residual hearing during cochlear implantation

  • Improving the nerve-electrode interface of the cochlear implant

Research projects

Student projects

Selected Publications

  1. Richardson, R. T., A. C. Thompson, A. K. Wise, and K. Needham. 2017. Challenges for the application of optical stimulation in the cochlea for the study and treatment of hearing loss. Expert Opinion on Biological Therapy. 17(2): 213-23.
  2. Wise, A. K., B. O. Flynn, P. J. Atkinson, J. B. Fallon, M. Nicholson, and R. Richardson. 2015. Regeneration of cochlear hair cells with Atoh1 gene therapy after noise-induced hearing loss Journal of Regenerative Medicine. 4(1): doi:http://dx.doi.org/10.4172/2325-9620.1000121. Full Text
  3. Richardson, R. T., and P. J. Atkinson. 2015. Atoh1 gene therapy in the cochlea for hair cell regeneration. Expert Opinion on Biological Therapy. 15(3): 417-30.
  4. Newbold, C., S. Mergen, R. Richardson, P. Seligman, R. Millard, R. Cowan, and R. Shepherd. 2014. Impedance changes in chronically implanted and stimulated cochlear implant electrodes. Cochlear Implants International. 15(4): 191-9.
  5. Irving, S., L. Gillespie, R. Richardson, D. Rowe, J. B. Fallon, and A. K. Wise. 2014. Electroacoustic stimulation: now and into the future. Biomed Research International. 2014: 350504. doi: 10.1155/2014/04. Full Text
  6. Gillespie, L. N., R. T. Richardson, B. A. Nayagam, and A. K. Wise. 2014. Treating hearing disorders with cell and gene therapy. Journal of Neural Engineering. 11(6): 065001. Full Text
  7. Atkinson, P. J., A. K. Wise, B. O. Flynn, B. A. Nayagam, and R. T. Richardson. 2014. Viability of long-term gene therapy in the cochlea. Scientific Reports. 4: 4733. doi: 10.1038/srep04733. Full Text
  8. Atkinson, P. J., A. K. Wise, B. O. Flynn, B. A. Nayagam, and R. T. Richardson. 2014. Hair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs. PLoS ONE. 9(7): e102077. doi: 10.1371/journal.pone.0102077. Full Text
  9. O’Leary, S. J., P. Monksfield, G. Kel, T. Connolly, M. A. Souter, A. Chang, P. Marovic, J. S. O’Leary, R. Richardson, and H. Eastwood. 2013. Relations between cochlear histopathology and hearing loss in experimental cochlear implantation. Hearing Research. 298: 27-35. doi: 10.1016/j.heares.2013.01.012. Full Text
  10. Atkinson, P. J., A. K. Wise, B. O. Flynn, B. A. Nayagam, C. R. Hume, S. J. O’Leary, R. K. Shepherd, and R. T. Richardson. 2012. Neurotrophin gene therapy for sustained neural preservation after deafness. PLoS ONE. 7(12): e52338. doi: 10.1371/journal.pone.0052338. Full Text

See more publications by Rachael Richardson in PubMed

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